Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.

نویسندگان

  • C Herens
  • J P Hermanne
  • F Tassin
  • M F Fassotte
  • A Thiry
  • M Jamar
  • N Schaaf-Lafontaine
  • G Fillet
  • L Koulischer
چکیده

Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.

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عنوان ژورنال:
  • Cancer genetics and cytogenetics

دوره 110 1  شماره 

صفحات  -

تاریخ انتشار 1999